Inclusion Criteria

A women is eligible if she meets the following:

• Is 25 years of age or older

• Is attending our clinic for routine cervical cancer screening following screening guidelines

• Has an intact cervix

• Is willing and able to provide documented informed consent

• Is willing and able to undergo colposcopy, biopsy, and endocervical curettage (ECC) within 12 weeks (< 84 days) from the baseline visit (if required)

• Is willing and able to allow collection of 2 cervical cytology specimens

Those Who Qualify Receive:

• Study related exams

• FDA - Approved Pap Test

• Compensation for time and travel

Exclusion Criteria

A women is ineligible for the study if she meets any of the following criteria:

• Is pregnant at the time of visit or plans to become pregnant within the following 12 weeks

• Has any known medical condition that, in the opinion of the investigator, would result in increased risk of bleeding at biopsy

• Has a known history of excisional or ablative therapy (e.g., LEEP, cone biopsy, cervical laser surgery, or cryotherapy) to the cervix in the last 12 months prior to baseline visit

• Had a cervical cytology specimen collected within the last 4 months

• Is currently participating in any diagnostic trial for cervical cancer

• Had a complete or partial hysterectomy, either supra cervical or involving removal of the cervix

• Is currently participating or planning to participate in any clinical trial for HPV treatment (for the duration of this study)

• Previous participation in this study